Tottenham suffered a second Premier League defeat of the season when they went down 1-0 to Manchester United on Sunday.

Henrikh Mkhitaryan’s first half strike was enough to see off Mauricio Pochettino’s side, who went into the game full of confidence having beaten Swansea 5-0 and CSKA Moscow 3-1 in the preceding eight days.

However, Spurs weren’t at their fluent best going forward, and have now suffered back-to-back away league defeats, having lost their unbeaten record to league leaders Chelsea in their previous away outing.

Nonetheless, Pochettino’s men still sit fifth in the table despite the defeat, three points behind Manchester City, but now only three points ahead of Jose Mourinho’s United in sixth.

Spurs will look to maintain that gap and possibly increase it when they host struggling Hull at White Hart Lane on Wednesday, with Mike Phelan’s side looking for only their second away league win of the campaign, having lost six in a row away from the KCOM Stadium.

However, the Tigers go into the match having drawn 3-3 at home to free-scoring Crystal Palace on Saturday, which means that they have lost just two of their last five games.

They come up against a solid Spurs side though on Wednesday night, and Pochettino will be hopeful that his side can secure an eighth league win of the season.

With another Premier League clash against Burnley coming up at the weekend, the Spurs boss may shuffle his pack on Wednesday, so here are THREE players who deserve a chance against Hull…

Harry Winks

Harry Winks’ one Premier League start this season saw him put in a man-of-the-match performance against West Ham last month.

The 20-year-old ran the show in the middle of the park, and also got his first league goal to equalise for Pochettino’s side.

With Dele Alli largely ineffective against United, Pochettino may decide to rest the England star, which could mean that Winks takes up his place, just like he did against West Ham.

A similar performance wouldn’t go amiss on Wednesday if he does make the starting eleven.

Eric Dier

With Mousa Dembele hauled off after 67 minutes against United with injury, it could open the door for Eric Dier to return to the defensive midfield position.

The England international has been in the side in recent weeks as a replacement for Toby Alderweireld in central defence, but the Belgian’s return relegated Dier to the bench against United.

However, Dembele’s injury could see him make an immediate return to the side, and perhaps plays in his most natural position for only the sixth time this season.

The 22-year-old has been excellent in the defensive midfield role for both club and country in the last 12 months and, if Pochettino feels that he needs two of those players in his side on Wednesday, then Dier could come into the starting line-up.

Moussa Sissoko

We’ve been highly critical of Moussa Sissoko since he moved to Tottenham from Newcastle in the summer, but you can’t fault his effort against United on Sunday.

The French international was introduced by Pochettino with half an hour still to play, and Sissoko gave Spurs the boost that was missing in the first 60 minutes, as he gave Matteo Darmian a torrid time down the right-hand-side.

The only thing missing from the 27-year-old was an end product, but it must give him and his manager confidence that he can step up when needed and give his team a boost when they are flagging.

Whether it’s enough for him to start on Wednesday remains to be seen, but he has certainly put himself in contention.