Top-of-the-table Burton Albion will be looking to maintain their two-point lead at the summit of League One when they make the trip to play-off hopefuls Sheffield United on Tuesday.
The Brewers were held to a goalless draw at home by Walsall at the weekend, allowing Wigan to move within two points of Nigel Clough’s side.
They come up against the Blades, who are just four points outside of the top-six despite a 2-0 defeat to Rochdale on Saturday.
Second-placed Wigan will look to close the gap further on Burton when they travel to fifth-placed Millwall.
The Latics are unbeaten since defeat to Blackpool in December, while the Lions have won three of their last five, but were held 1-1 by Doncaster last time out.
Third-placed Gillingham will look to recover from back-to-back defeats when they travel to lowly Fleetwood. The Gills have been beaten 2-1 in successive games by teams at the wrong end of the table – Oldham and Chesterfield.
Walsall will hope to end a run of four games without a win when they host mid-table Scunthorpe at the Banks’ Stadium.
In the final play-off spot despite a shock 2-1 home defeat by Fleetwood at the weekend are Coventry City, and they make the trip north to face in-form Barnsley, who have won nine of their last 11 in the league and are just three points behind the Sky Blues in sixth.
Meanwhile, seventh-placed Bradford are just one point behind Coventry and welcome Colchester to Valley Parade, with the visitors bottom of the table and ten points from safety.
Eighth-placed Southend host second-from-bottom Crewe, looking to bounce back from a 3-1 loss to Port Vale on Friday night, while Vale travel to another team in trouble, 22nd-placed Oldham.
12th-placed Swindon welcome 17th-placed Doncaster to the County Ground on the back of a run of three straight victories, while Rochdale welcome 21st-placed Shrewsbury to Spotland, and Bury and Peterborough, who both have 44 points, meet at Gigg Lane.
Finally, two sides just above the relegation zone meet at the Proact Stadium as Chesterfield host Blackpool.