Leaders Coventry face in-form Bradford at Valley Parade looking to extend their unbeaten run to 10 matches.
The Bantams have been on somewhat of a good run lately, they are undefeated in their last eight games and know that a win could take them into the top-three.
But they will have to beat the table toppers who are full of confidence after beating promotion rivals Gillingham 4-1 at the weekend.
The Gills will be looking to bounce back from that defeat with a victory at home to Rochdale.
Justin Edinburgh’s side have the best record in the division, collecting 23 points from a possible 27, whilst Dale have lost but won just one of their last six.
Colchester have conceded the most goals in League One this season, and have leaked 13 in their last four games, all of which they have failed to win.
However, Tony Humes’ side will fancy themselves against the league’s basement boys Crewe Alexandra, who were humbled 5-1 by Peterborough at the weekend, and will be looking for only their fourth win of the season.
Fleetwood will be on cloud nine after a 5-1 win against fellow strugglers Swindon on Saturday, a win that lifted them out of the relegation zone.
On Tuesday, they face Neil Harris’ Millwall who are six games unbeaten and arrive at Highbury on the back of a fine 4-1 win over Colchester. The Lions could jump into the play-off places with a win.
Swindon have no time to suffer in silence after their thrashing as they host third-placed Walsall.
The Robins could climb out of the drop zone with a win, but the Saddlers are unbeaten in eight league matches on the road this term.
Southend are within touching distance of the play-off places and will be looking to make it two wins in as many games after Saturday’s narrow 1-0 win over Blackpool.
Their opposition this time out is David Dunn’s Oldham side who have won only one of their last four games and are hovering just above the relegation zone. However, the Lactics could go as high as 16th with a win.
Graham Westley’s Peterborough are League One’s top scorers this season, and welcome fourth bottom Barnsley to the ABAX stadium.
Both sides managed to pick up wins this weekend, though Posh’s 5-1 thumping of Crewe was slightly more emphatic than the Tykes 89th minute 2-1 win against Oldham which ended a horrific eight-game losing streak.
Port Vale have won their last three games, and Rob Page’s side will be confident of extending that winning run to four games when they welcome second bottom side Blackpool to Vale Park.
Following a five-game unbeaten run, the Seasiders have lost their last four games and sit just three points above Crewe at the bottom of the table.
Wigan could lift themselves into the automatic promotion places with a win over fifth paced Burton Albion, and they are well placed to do so, having extended their unbeaten run to 11 games with a 1-0 win over Shrewsbury at the weekend.
They face Jimmy Floyd Hasselbaink’s side, who could also move into the automatic promotion places with a win and are looking to bounce back following a disappointing 1-0 defeat at Bury in their last outing.
All League One matches:
Bradford v Coventry
Bury v Scunthorpe
Colchester v Crewe
Doncaster v Chesterfield
Fleetwood v Milwall
Gillingham v Rochdale
Oldham v Southend
Peterborough v Barnsley
Port Vale v Blackpool
Sheffield United v Shrewsbury
Swindon v Walsall
Wigan v Burton