Manchester United can secure their spot in the last-16 of the Champions League if they beat PSV Eindhoven at Old Trafford.
After their slender 1-0 win over CSKA Moscow last time out, the Red Devils top a tightly contested group with seven points from four matches.
Their Dutch visitors, who are the only team to beat the Red Devils so far with a 2-1 win in the opening match, are second and a point behind their hosts.
Phillip Cocu’s side have won both of their home matches but have been defeated in their two away trips, and with United holding a 100% record in front of their own fans in Group B, Louis van Gaal will be confident of getting the job done on Wednesday night.
With five wins and two draws from seven Premier League matches at the Theatre of Dreams, LvG looks to be turning his side’s home into the fortress it once was.
Just like United, who are second in the Premier League table, PSV are going well in their domestic competition, sitting third in the Eredivisie with just one defeat from 13 matches.
These two sides have only met in Manchester twice before, with United winning a 1984 UEFA Cup match 1-0 and a 2000 Champions League group game 3-1.
Captain Wayne Rooney is available again after missing Saturday’s win at Watford due to illness.
But despite being back to full health, Van Gaal has said there’s no guarantee that he will restore his skipper to the starting XI.
Marouane Fellaini and Anthony Martial are also back, but Ander Herrera, Phil Jones, Michael Carrick and Antonio Valencia are out.
Cocu also has some injury worries with Menno Koch out after rupturing his anterior cruciate ligament.
Jetro Willems and Maxime Lestienne are also expected to miss out.
Group Position: Manchester United – 1st (7 pts); PSV – 2nd (6 pts)
Last Meeting: PSV 2-1 Manchester United, September 15, 2015
Key Men: Manchester United – Memphis Depay; PSV – Luuk de Jong
Form (all competitions): Manchester United – DLDWWW; PSV – WWWWWD
Shoot Says: Manchester United 2-0 PSV