The Hammers will hope to build on their impressive display against Chelsea and face a Crystal Palace side without a league win in 2016.
West Ham United have had a spectacular season so far and are real challengers for Champions League qualification.
The Hammers are unbeaten in five league games and have players coming into form at just the right time. Dimitri Payet has been a revelation for the London club and the midfielder will still be in high spirits from his international performance midweek.
However, manager Slaven Bilic has voiced his concerns over players returning late from international duty and worries this game may have come too soon.
Opposing boss Alan Pardew will certainly hope to capitalise on any West Ham fatigue as he looks for his side’s first win this calendar year.
The Eagles have plummeted down the table since enduring this rotten run of form and are in desperate need of a win to avoid being dragged into a relegation battle.
Bilic has confirmed central defender James Tomkins will return to the side after recent injury problems have kept him out.
Fellow defenders James Collins and Sam Byram will not be fit for Saturday however and join long-term absentee Carl Jenkinson in the stands.
Palace will be slightly worried by the fitness of Yohan Cabaye, Emmanuel Adebayor and Miles Jedinak who are all doubts for the weekend.
Striker Connor Wickham is also a big doubt for the Eagle’s visit to Upton Park.
James McArthur (knee), Kwesi Appiah (knee) and Marouane Chamakh (hip) are also continuing their respective recoveries.
League Positions: West Ham – 5th (50 pts); Crystal Palace – 16th (33pts)
Form: West Ham – LDWWWD; Crystal Palace – DLLDLL
Previous Meeting: Crystal Palace 1-3 West Ham – October 17, 2015; Premier League
Key Players: West Ham – Dimitri Payet; Crystal Palace – Scott Dann
Shoot Says: West Ham 2-0 Crystal Palace