Leaders Brighton face another tough test as they look to extend their unbeaten run to 15 games when they travel to Hillsborough to take on Sheffield Wednesday.
The Owls are unbeaten in 10 matches in all competitions and a win here could see them jump into the top-six.
Despite remaining undefeated, the Seagulls will be keen to add three points to their tally as they have drawn five of their last seven outings.
Brentford take on second-placed Hull having had an upturn in fortunes since they parted company with Marinus Dijkhuizen in September with caretaker manager Lee Carsley guiding the Bees to four wins from his six games in charge.
The Tigers are unbeaten in eight, also on a four-game winning run, and Steve Bruce’s team know that a win could take them to the top of the table if other results go their way.
Burnley could also claim top spot if Hull and Brighton fail to win, but they will have to beat a Fulham side that will be high on confidence after a fine 4-1 win against Bristol City at the weekend.
Both sides are unbeaten in their last five games, but the Clarets will have the advantage on their own patch, as they’ve only lost once at Turf Moor this season.
In-form Derby host QPR at the iPro, looking to extend their unbeaten run to 10 matches.
The Rams, who now sit three points off the top, have only lost once all season and face a side which has triumphed in just two of their past nine outings.
R’s boss Chris Ramsey is under pressure but knows a third away win of the season will quiet his critics for the time being, at least.
Steve Evans’ reign at Leeds United has failed to take off as yet and his side conceded twice inside the first six minutes to condemn him to defeat in his first home match in charge against Blackburn last week.
The White boss will be hoping to secure his first win against a Cardiff team who have only scored once in their last four games.
However, the Bluebirds are unbeaten in six matches,have not conceded in four and could move into the play-off places with a win.
Rotherham are currently bottom of the Championship without a win in five, and won’t be too optimistic of picking up three points when they travel to the Riverside Stadium to take on Aitor Karanka’s Middlesbrough.
The Teesiders will be on cloud nine after following up their penalty shootout victory against Manchester United, with a 3-0 victory against Charlton.
Charlton’s run of 10 games without a win has seen them drop from the play-off spots to 23rd in the table.
Now interim boss Karel Fraeye will be hoping to break the winless streak as he takes the Addicks to face an MK Dons side who hover just a point above them in the relegation zone, having conceded seven without reply in their last three outings.
The Dons have won twice at home though this term, whilst Charlton have yet to win on the road.
All Championship Matches:
Birmingham v Blackburn
Brentford v Hull
Bristol City v Wolves
Burnley v Fulham
Derby v QPR
Ipswich v Bolton
Leeds v Cardiff
Middlesbrough v Rotherham
MK Dons v Charlton
Preston v Notts Forest
Sheffield Wednesday v Brighton
Reading v Huddersfield (20:00)